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Serum Biomarkers in Patients with Relapsing...
Journal article

Serum Biomarkers in Patients with Relapsing Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss)

Abstract

INTRODUCTION: Previous studies suggest a role for eotaxin-3, TARC/CCL17 and IgG4 in newly-diagnosed patients with eosinophilic granulomatosis with polyangiitis (EGPA, Churg-Strauss) with highly active disease. The role of these biomarkers in relapsing disease is unclear. METHODS: Serum levels of TARC/CCL17, eotaxin-3, IgG4, and IgG4/IgG ratio were determined in serum samples from a longitudinal cohort of patients with EGPA (105 visits of 25 …

Authors

Dejaco C; Oppl B; Monach P; Cuthbertson D; Carette S; Hoffman G; Khalidi N; Koening C; Langford C; McKinnon-Maksimowicz K

Journal

PLOS ONE, Vol. 10, No. 3,

Publisher

Public Library of Science (PLoS)

DOI

10.1371/journal.pone.0121737

ISSN

1932-6203