Journal article
Previous inflammation alters the response of the rat colon to stress
Abstract
BACKGROUND & AIMS: Patients with inflammatory bowel disease have symptoms of irritable bowel syndrome (IBS) with a higher than expected prevalence. Stress is an important factor in the pathogenesis of IBS. Thus, previous inflammation may predispose to IBS by rendering the bowel more susceptible to the impact of stress. The aim of this study was to examine the effect of previous colitis on stress-induced responses in rats.
METHODS: Acute colitis …
Authors
Collins S; McHugh K; Jacobson K; Khan I; Riddell R; Murase K; Weingarten H
Journal
Gastroenterology, Vol. 111, No. 6, pp. 1509–1515
Publisher
Elsevier
Publication Date
12 1996
DOI
10.1016/s0016-5085(96)70012-4
ISSN
0016-5085