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The Evolutionary Origins of Eukaryotic Protein...
Journal article

The Evolutionary Origins of Eukaryotic Protein Disulfide Isomerase Domains: New Evidence from the Amitochondriate Protist Giardia lamblia

Abstract

A phylogenetic analysis of protein disulfide isomerase (PDI) domain evolution was performed with the inclusion of recently reported PDIs from the amitochondriate protist Giardia lamblia, yeast PDIs that contain a single thioredoxin-like domain, and PDIs from a diverse selection of protists. We additionally report and include two new giardial PDIs, each with a single thioredoxin-like domain. Inclusion of protist PDIs in our analyses revealed …

Authors

McArthur AG; Knodler LA; Silberman JD; Davids BJ; Gillin FD; Sogin ML

Journal

Molecular Biology and Evolution, Vol. 18, No. 8, pp. 1455–1463

Publisher

Oxford University Press (OUP)

Publication Date

August 1, 2001

DOI

10.1093/oxfordjournals.molbev.a003931

ISSN

0737-4038