Journal article
Nrf2b, Novel Zebrafish Paralog of Oxidant-responsive Transcription Factor NF-E2-related Factor 2 (NRF2)*
Abstract
NF-E2-related factor 2 (NRF2; also called NFE2L2) and related NRF family members regulate antioxidant defenses by activating gene expression via antioxidant response elements (AREs), but their roles in embryonic development are not well understood. We report here that zebrafish (Danio rerio), an important developmental model species, possesses six nrf genes, including duplicated nrf1 and nrf2 genes. We cloned a novel zebrafish nrf2 paralog, …
Authors
Timme-Laragy AR; Karchner SI; Franks DG; Jenny MJ; Harbeitner RC; Goldstone JV; McArthur AG; Hahn ME
Journal
Journal of Biological Chemistry, Vol. 287, No. 7, pp. 4609–4627
Publisher
Elsevier
Publication Date
February 2012
DOI
10.1074/jbc.m111.260125
ISSN
0021-9258