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Gene expression changes during Giardia–host cell...
Journal article

Gene expression changes during Giardia–host cell interactions in serum-free medium

Abstract

Serial Analysis of Gene Expression (SAGE) was used to quantify transcriptional changes in Giardia intestinalis during its interaction with human intestinal epithelial cells (IECs, HT-29) in serum free M199 medium. Transcriptional changes were compared to those in trophozoites alone in M199 and in TYI-S-33 Giardia growth medium. In total, 90 genes were differentially expressed, mainly those involved in cellular redox homeostasis, metabolism and …

Authors

Ferella M; Davids BJ; Cipriano MJ; Birkeland SR; Palm D; Gillin FD; McArthur AG; Svärd S

Journal

Molecular and Biochemical Parasitology, Vol. 197, No. 1-2, pp. 21–23

Publisher

Elsevier

Publication Date

October 2014

DOI

10.1016/j.molbiopara.2014.09.007

ISSN

0166-6851