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Exercise training increases branched-chain oxoacid...
Journal article

Exercise training increases branched-chain oxoacid dehydrogenase kinase content in human skeletal muscle

Abstract

The branched-chain oxoacid dehydrogenase complex (BCOAD) is rate determining for the oxidation of branched-chain amino acids (BCAAs) in skeletal muscle. Exercise training blunts the acute exercise-induced activation of BCOAD (BCOADa) in human skeletal muscle (McKenzie S, Phillips SM, Carter SL, Lowther S, Gibala MJ, Tarnopolsky MA. Am J Physiol Endocrinol Metab 278: E580-E587, 2000); however, the mechanism is unknown. We hypothesized that …

Authors

Howarth KR; Burgomaster KA; Phillips SM; Gibala MJ

Journal

AJP Regulatory Integrative and Comparative Physiology, Vol. 293, No. 3, pp. r1335–r1341

Publisher

American Physiological Society

Publication Date

9 2007

DOI

10.1152/ajpregu.00115.2007

ISSN

0363-6119