Journal article
Mathematical model for chemotherapeutic drug efficacy in arresting tumour growth based on the cancer stem cell hypothesis
Abstract
OBJECTIVE: Cancer stem cells have been identified as the growth root for various malignant tumours and are thought to be responsible for cancer recurrence following treatment.
MATERIALS AND METHODS: Here, a predictive mathematical model for the cancer stem cell hypothesis is used to understand tumour responses to chemotherapeutic drugs and judge the efficacy of treatments in arresting tumour growth. The impact of varying drug efficacies on …
Authors
Ganguly R; Puri IK
Journal
Cell Proliferation, Vol. 40, No. 3, pp. 338–354
Publisher
Wiley
Publication Date
6 2007
DOI
10.1111/j.1365-2184.2007.00434.x
ISSN
0960-7722