Journal article
Vascular Endothelial Growth Factor Polymorphisms and Esophageal Cancer Prognosis
Abstract
PURPOSE: Vascular endothelial growth factor (VEGF) promotes angiogenesis and vascular permeability. The VEGF gene is polymorphic. We investigated the prognostic significance of three VEGF single nucleotide polymorphisms (SNP) in esophageal cancer.
EXPERIMENTAL DESIGN: Three hundred sixty-one patients were genotyped for three VEGF SNPs (-460T/C, 405G/C, and 936C/T) using DNA extracted from prospectively collected blood samples. The association …
Authors
Bradbury PA; Zhai R; Ma C; Xu W; Hopkins J; Kulke MJ; Asomaning K; Wang Z; Su L; Heist RS
Journal
Clinical Cancer Research, Vol. 15, No. 14, pp. 4680–4685
Publisher
American Association for Cancer Research (AACR)
Publication Date
July 15, 2009
DOI
10.1158/1078-0432.ccr-09-0192
ISSN
1078-0432