Differential regulation of myofibrillar and mitochondrial protein synthesis following acute endurance exercise (702.3)

Endurance exercise leads to rapid transcriptional‐ and translational‐mediated remodeling in skeletal muscle. The purpose of this study was to investigate the role of the mechanistic target of rapamycin (mTORC1) in the molecular regulation of myofibrillar and mitochondrial protein synthesis in the first 6h after endurance exercise. Female C57BL/6 mice performed one‐hour of treadmill running after administration of rapamycin or vehicle. A …