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Effect of Standard Radiotherapy With Cisplatin vs...
Journal article

Effect of Standard Radiotherapy With Cisplatin vs Accelerated Radiotherapy With Panitumumab in Locoregionally Advanced Squamous Cell Head and Neck Carcinoma: A Randomized Clinical Trial

Abstract

IMPORTANCE: The Canadian Cancer Trials Group study HN.6 is the largest randomized clinical trial to date comparing the concurrent administration of anti-epidermal growth factor receptor (EGFR) monoclonal antibodies with radiotherapy (RT) to standard chemoradiotherapy in locoregionally advanced squamous cell carcinoma of the head and neck (LA-SCCHN). OBJECTIVE: To compare progression-free survival (PFS) in patients with LA-SCCHN treated with …

Authors

Siu LL; Waldron JN; Chen BE; Winquist E; Wright JR; Nabid A; Hay JH; Ringash J; Liu G; Johnson A

Journal

JAMA Oncology, Vol. 3, No. 2, pp. 220–226

Publisher

American Medical Association (AMA)

Publication Date

February 1, 2017

DOI

10.1001/jamaoncol.2016.4510

ISSN

2374-2437