Journal article
Limitations of single slice dynamic contrast enhanced MR in pharmacokinetic modeling of bone sarcomas
Abstract
BACKGROUND: Single slice dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) appears to provide perfusion data about sarcomas in vivo that correlate with tumor necrosis on equivalent pathological sections. However, sarcomas are heterogeneous and therefore single slice DCE-MRI may not correlate with total tumor necrosis.
PURPOSE: To determine whether changes in pharmacokinetic modeling of DCE-MRI, during chemotherapy for primary bone …
Authors
Toms AP; White LM; Kandel R; Bleakney RR; Noseworthy M; Lee S; Blackstein ME; Wunder J
Journal
Acta Radiologica, Vol. 50, No. 5, pp. 512–520
Publisher
SAGE Publications
Publication Date
June 2009
DOI
10.1080/02841850902922761
ISSN
0284-1851