Journal article
Treatment with anti‐OX40L or anti‐TSLP does not alter the frequency of T regulatory cells in allergic asthmatics
Abstract
OX40-OX40L interactions and thymic stromal lymphopoietin (TSLP) are important in the induction and maintenance of Th2 responses in allergic disease, whereas T regulatory cells (Treg) have been shown to suppress pro-inflammatory Th2 responses. Both OX40L and TSLP have been implicated in the negative regulation of Treg. The effect of anti-asthma therapies on Treg is not well known. Our aim was to assess the effects of two monoclonal antibody …
Authors
Baatjes AJ; Smith SG; Dua B; Watson R; Gauvreau GM; O'Byrne PM
Journal
Allergy, Vol. 70, No. 11, pp. 1505–1508
Publisher
Wiley
Publication Date
November 2015
DOI
10.1111/all.12708
ISSN
0001-5148