Polymeric Immunoglobulin Receptor is synthesized locally in the rodent vagina and under the control of sex hormones

The aim of this study was to identify the origin of Polymeric Immunoglobulin Receptor (plgR) present in the vagina and to examine the control by sex hormones of vaginal plgR levels. PlgR message corresponding in size to that previously reported in liver and uterus was detected by Northern blot analysis of total RNA from vagina. When levels of plgR mRNA were examined in the vagina at different stages of the estrous cycle, message levels were …