Journal article
A Genome-wide Association Study Identifies Risk Alleles in Plasminogen and P4HA2 Associated with Giant Cell Arteritis
Abstract
Giant cell arteritis (GCA) is the most common form of vasculitis in individuals older than 50 years in Western countries. To shed light onto the genetic background influencing susceptibility for GCA, we performed a genome-wide association screening in a well-powered study cohort. After imputation, 1,844,133 genetic variants were analyzed in 2,134 case subjects and 9,125 unaffected individuals from ten independent populations of European …
Authors
Carmona FD; Vaglio A; Mackie SL; Hernández-Rodríguez J; Monach PA; Castañeda S; Solans R; Morado IC; Narváez J; Ramentol-Sintas M
Journal
American Journal of Human Genetics, Vol. 100, No. 1, pp. 64–74
Publisher
Elsevier
Publication Date
January 2017
DOI
10.1016/j.ajhg.2016.11.013
ISSN
0002-9297