Journal article
The role of serotonin and its receptors in activation of immune responses and inflammation
Abstract
Serotonin or 5-hydroxytryptamine (5-HT) is a neurotransmitter and hormone that contributes to the regulation of various physiological functions by its actions in the central nervous system (CNS) and in the respective organ systems. Peripheral 5-HT is predominantly produced by enterochromaffin (EC) cells of the gastrointestinal (GI) tract. These gut-resident cells produce much more 5-HT than all neuronal and other sources combined, establishing …
Authors
Shajib MS; Khan WI
Journal
Acta Physiologica, Vol. 213, No. 3, pp. 561–574
Publisher
Wiley
Publication Date
March 2015
DOI
10.1111/apha.12430
ISSN
1748-1708