Do Deeper Sections Increase the Frequency of Detection of Serous Tubal Intraepithelial Carcinoma (STIC) in the “Sectioning and Extensively Examining the FIMbriated End” (SEE-FIM) Protocol?

Studies have suggested serous tubal intraepithelial carcinoma (STIC) of the fallopian tube to be a putative precursor to ovarian and peritoneal serous carcinoma. It has been recommended that resected fallopian tube specimens should be rigorously examined for STIC, especially in women at high risk of serous carcinoma, such as those with BRCA mutations or with a strong family history. The SEE-FIM protocol allows for the greatest surface area of …