High Pressure Pulsatile Lavage of Contaminated Human Tibiae: An In Vitro Study

OBJECTIVE: This study was designed to examine the effect of high pressure pulsatile lavage (HPPL) on bone destruction and propagation of bacteria in experimentally contaminated human tibiae. METHODS: Using an in vitro model, nine human tibiae from above-knee amputations were tested. A mid-diaphyseal tibial shaft fracture was created, and each end of the fracture was contaminated with bacteria (six tibiae with Staphylococcus aureus, three tibiae …