Journal article
Buccal mucosal irritation studies of sublingual apomorphine film (APL-130277) in Syrian golden hamsters
Abstract
AIM: Determine the potential for cheek pouch buccal mucosa irritation in hamsters following administration of apomorphine hydrochloride film (APL-130277).
METHODS: Three studies were conducted with Syrian golden hamsters. (First study, four hamsters received APL-130277 three times a day [TID] for 7 days. Second study, four hamsters received APL-130277 once a day [QD] for days 1-3, twice a day [BID] for days 4-7 and TID for days 8-21. Third …
Authors
Bilbault T; Taylor S; Walker R; Grundy SL; Pappert EJ; Agro A
Journal
Therapeutic Delivery, Vol. 7, No. 9, pp. 611–618
Publisher
Taylor & Francis
Publication Date
September 2016
DOI
10.4155/tde-2016-0043
ISSN
2041-5990