The orthopaedic trauma literature: an evaluation of statistically significant findings in orthopaedic trauma randomized trials

BackgroundEvidence-based medicine posits that health care research is founded upon clinically important differences in patient centered outcomes. Statistically significant differences between two treatments may not necessarily reflect a clinically important difference. We aimed to quantify the sample sizes and magnitude of treatment effects in a review of orthopaedic randomized trials with statistically significant findings.MethodsWe conducted …