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Bigger Data, Bigger Problems
Journal article

Bigger Data, Bigger Problems

Abstract

Clinical studies frequently lack the ability to reliably answer their research questions because of inadequate sample sizes. Underpowered studies are subject to multiple sources of bias, may not represent the larger population, and are regularly unable to detect differences between treatment groups. Most importantly, an underpowered study can lead to incorrect conclusions. Big data can be used to address many of these concerns, enabling …

Authors

Slobogean GP; Giannoudis PV; Frihagen F; Forte ML; Morshed S; Bhandari M

Journal

Journal of Orthopaedic Trauma, Vol. 29, No. &NA;, pp. s43–s46

Publisher

Wolters Kluwer

Publication Date

December 2015

DOI

10.1097/bot.0000000000000463

ISSN

0890-5339