Journal article
Bigger Data, Bigger Problems
Abstract
Clinical studies frequently lack the ability to reliably answer their research questions because of inadequate sample sizes. Underpowered studies are subject to multiple sources of bias, may not represent the larger population, and are regularly unable to detect differences between treatment groups. Most importantly, an underpowered study can lead to incorrect conclusions. Big data can be used to address many of these concerns, enabling …
Authors
Slobogean GP; Giannoudis PV; Frihagen F; Forte ML; Morshed S; Bhandari M
Journal
Journal of Orthopaedic Trauma, Vol. 29, No. &NA;, pp. s43–s46
Publisher
Wolters Kluwer
Publication Date
December 2015
DOI
10.1097/bot.0000000000000463
ISSN
0890-5339