Journal article
The Commensal Bacterium Faecalibacterium prausnitzii Is Protective in DNBS-induced Chronic Moderate and Severe Colitis Models
Abstract
BACKGROUND: The abundance of Faecalibacterium prausnitzii, an abundant and representative bacterium of Firmicutes phylum, has consistently been observed to be lower in patients with Crohn's disease than in healthy individuals. We have shown that both F. prausnitzii and its culture supernatant (SN) have anti-inflammatory and protective effects in a TNBS-induced acute colitis mouse model. Here, we tested the effects of both F. prausnitzii and its …
Authors
Martín R; Chain F; Miquel S; Lu J; Gratadoux J-J; Sokol H; Verdu EF; Bercik P; Bermúdez-Humarán LG; Langella P
Journal
Inflammatory Bowel Diseases, Vol. 20, No. 3, pp. 417–430
Publisher
Oxford University Press (OUP)
Publication Date
March 2014
DOI
10.1097/01.mib.0000440815.76627.64
ISSN
1078-0998