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The microbiota–gut–brain axis in gastrointestinal...
Journal article

The microbiota–gut–brain axis in gastrointestinal disorders: stressed bugs, stressed brain or both?

Abstract

The gut-brain axis is the bidirectional communication between the gut and the brain, which occurs through multiple pathways that include hormonal, neural and immune mediators. The signals along this axis can originate in the gut, the brain or both, with the objective of maintaining normal gut function and appropriate behaviour. In recent years, the study of gut microbiota has become one of the most important areas in biomedical research. …

Authors

De Palma G; Collins SM; Bercik P; Verdu EF

Journal

The Journal of Physiology, Vol. 592, No. 14, pp. 2989–2997

Publisher

Wiley

Publication Date

July 15, 2014

DOI

10.1113/jphysiol.2014.273995

ISSN

0022-3751