Journal article
Lactobacillus paracasei normalizes muscle hypercontractility in a murine model of postinfective gut dysfunction
Abstract
BACKGROUND & AIMS: The effects of probiotics on gut dysfunction in postinfective irritable bowel syndrome are unknown. We tested whether probiotics influence persistent muscle hypercontractility in mice after recovery from infection with Trichinella spiralis and analyzed the underlying mechanisms.
METHODS: Mice were gavaged with Lactobacillus paracasei, Lactobacillus johnsonii, Bifidobacterium longum, or Bifidobacterium lactis in spent culture …
Authors
Verdú EF; Bercík P; Bergonzelli GE; Huang X-X; Blennerhasset P; Rochat F; Fiaux M; Mansourian R; Corthésy-Theulaz I; Collins SM
Journal
Gastroenterology, Vol. 127, No. 3, pp. 826–837
Publisher
Elsevier
Publication Date
September 2004
DOI
10.1053/j.gastro.2004.06.007
ISSN
0016-5085
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AnimalsChemokine CCL5Cyclooxygenase 2DinoprostoneFemaleGastrointestinal MotilityIsoenzymesJejunumLactobacillusMiceModels, AnimalMuscle ContractionMuscle, SmoothProbioticsProstaglandin-Endoperoxide SynthasesRecovery of FunctionSpasmTh2 CellsTransforming Growth Factor betaTrichinella spiralisTrichinellosis