Journal article
A unique BRCA1 mutation identified in Mongolia
Abstract
This is a case report of genetic assessment conducted on a family residing in the third world where two sisters have presented with early onset ovarian cancer. Protein truncation testing and DNA sequencing identified a unique mutation on exon 11 (3452delA) of the BRCA1 gene. Buccal swab testing of three siblings and three offspring showed that half of the family members carried the same mutation. Currently, genetic testing in third-world …
Authors
Elit L; Jack E; Kwan E; Baigal G; Narod S
Journal
International Journal of Gynecological Cancer, Vol. 11, No. 3, pp. 241–243
Publisher
Elsevier
Publication Date
May 8, 2001
DOI
10.1046/j.1525-1438.2001.01020.x
ISSN
1048-891X