Journal article
The impact of prophylactic salpingo-oophorectomy on menopausal symptoms and sexual function in women who carry a BRCA mutation
Abstract
OBJECTIVE: Prophylactic salpingo-oophorectomy is recommended to women who carry a BRCA1 or BRCA2 mutation to reduce the risks of breast, ovarian and fallopian tube cancer. We measured the impact of prophylactic salpingo-oophorectomy on menopausal symptoms and sexual functioning in women with a BRCA mutation.
METHODS: Women who underwent prophylactic salpingo-oophorectomy between October 1, 2002 and June 26, 2008 for a known BRCA1 or BRCA2 …
Authors
Finch A; Metcalfe KA; Chiang JK; Elit L; McLaughlin J; Springate C; Demsky R; Murphy J; Rosen B; Narod SA
Journal
Gynecologic Oncology, Vol. 121, No. 1, pp. 163–168
Publisher
Elsevier
Publication Date
April 2011
DOI
10.1016/j.ygyno.2010.12.326
ISSN
0090-8258
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdultAgedFallopian Tube NeoplasmsFemaleGenes, BRCA1Genes, BRCA2Genetic Predisposition to DiseaseGerm-Line MutationHormone Replacement TherapyHumansMenopauseMiddle AgedOvarian NeoplasmsOvariectomyPatient SatisfactionQuality of LifeSalpingostomySexual Dysfunction, PhysiologicalSurveys and Questionnaires