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A systematic meta‐analysis of randomized...

Journal article

A systematic meta‐analysis of randomized controlled trials of adjuvant chemotherapy for localized resectable soft‐tissue sarcoma

Abstract

AbstractBACKGROUND.The use of adjuvant chemotherapy to treat adults with localized resectable soft‐tissue sarcoma remains controversial. The objective of this systematic review was to update the 1997 meta‐analysis of randomized controlled trials (RCTs) to reassess the efficacy of doxorubicin‐based chemotherapy with respect to recurrence and survival.METHODS.A comprehensive literature search was performed to identify RCTs of adjuvant …

Authors

Pervaiz N; Colterjohn N; Farrokhyar F; Tozer R; Figueredo A; Ghert M

Journal

Cancer, Vol. 113, No. 3, pp. 573–581

Publisher

Wiley

Publication Date

August 2008

DOI

10.1002/cncr.23592

ISSN

0008-543X

Associated Experts

Forough Farrokhyar

Professor (Part-Time), Faculty of Health Sciences

Michelle Ghert

Professor (Part-Time), Faculty of Health Sciences

Richard Tozer

Associate Professor, Faculty of Health Sciences

Labels

Medical Subject Headings (MeSH)

Algorithms Antineoplastic Combined Chemotherapy Protocols Chemotherapy, Adjuvant Combined Modality Therapy Doxorubicin Humans Neoplasm Metastasis Neoplasm Recurrence, Local Odds Ratio Randomized Controlled Trials as Topic Sarcoma Survival Analysis

Fields of Research (FoR)

3211 Oncology and carcinogenesis 4206 Public health

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