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Use of Calcium Pump Inhibitors in the Study of...
Journal article

Use of Calcium Pump Inhibitors in the Study of Calcium Regulation in Smooth Muscle

Abstract

The study of the relative roles of the plasma membrane (PM) and the sarcoplasmic reticulum (SR) Ca2+ pumps in the regulation of internal Ca2+ has been limited in the past due in part to the lack of selective inhibitors for either Ca2+ pump. Recently, three compounds have been discovered which appear to be selective SR Ca2+ pump inhibitors: thapsigargin (TSG), cyclopiazonic acid (CPA), and 2,5-di-(tert-butyl)-1,4-benzohydroquinone. Contractility …

Authors

Darby PJ; Kwan C-Y; Daniel EE

Journal

Neurosignals, Vol. 2, No. 5, pp. 293–304

Publisher

Karger Publishers

Publication Date

1993

DOI

10.1159/000109510

ISSN

1424-862X