Journal article
Further localization of X-linked hydrocephalus in the chromosomal region Xq28.
Abstract
X-linked hydrocephalus (HSAS) is the most frequent genetic form of hydrocephalus. Clinical symptoms of HSAS include hydrocephalus, mental retardation, clasped thumbs, and spastic paraparesis. Recently we have assigned the HSAS gene to Xq28 by linkage analysis. In the present study we used a panel of 18 Xq27-q28 marker loci to further localize the HSAS gene in 13 HSAS families of different ethnic origins. Among the Xq27-q28 marker loci used, …
Authors
Willems PJ; Vits L; Raeymaekers P; Beuten J; Coucke P; Holden JJ; Van Broeckhoven C; Warren ST; Sagi M; Robinson D
Journal
American Journal of Human Genetics, Vol. 51, No. 2, pp. 307–315
Publication Date
August 1992
ISSN
0002-9297