Journal article
Lipoxins and Aspirin-Triggered Lipoxins in Airway Responses
Abstract
Leukotrienes (LT) and prostaglandins (PG) have been implicated as proinflammatory mediators in asthma [1], while lipoxins (LX) are a distinct class of eicosanoids that carry unique counter-regulatory actions [2]. Analyses of the time course of appearance of eicosanoids during acute inflammation has revealed the early coordinate appearance of LT and PG with leukocyte recruitment followed by LX during resolution [3]. LX’s are generated in human …
Authors
Levy BD; De Sanctis GT; Devchand PR; Kim E; Ackerman K; Schmidt B; Szczeklik W; Drazen JM; Serhan CN
Journal
Advances in Experimental Medicine and Biology, Vol. 525, , pp. 19–23
Publisher
Springer Nature
Publication Date
2003
DOI
10.1007/978-1-4419-9194-2_5
ISSN
0065-2598