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Impact of High-Dose Vitamin D3 Supplementation in...
Journal article

Impact of High-Dose Vitamin D3 Supplementation in Patients with Crohn’s Disease in Remission: A Pilot Randomized Double-Blind Controlled Study

Abstract

AimTo assess the tolerability and efficacy of high-dose vitamin D3 in patients with Crohn’s disease (CD).MethodsThis was a randomized, double-blind placebo-controlled trial of high-dose vitamin D3 at 10,000 IU daily (n = 18) compared to 1000 IU daily (n = 16) for 12 months in patients with CD in remission. The primary outcome was change in serum 25-hydroxy-vitamin D levels. Secondary outcomes included clinical relapse rates and changes in mood …

Authors

Narula N; Cooray M; Anglin R; Muqtadir Z; Narula A; Marshall JK

Journal

Digestive Diseases and Sciences, Vol. 62, No. 2, pp. 448–455

Publisher

Springer Nature

Publication Date

February 2017

DOI

10.1007/s10620-016-4396-7

ISSN

0163-2116