Chemical and biological reactivity of insoluble nickel compounds and the bioinorganic chemistry of nickel.

The basic concepts describing the surface properties of binary metal compounds at solid-solution interfaces are reviewed. For hydrated surfaces, the development of surface charge is dependent on pH and the extent of specific adsorption of cations and anions. It is concluded from data on haemolysis of human erythrocytes, and surface adsorption of proteins and cations that surface passivity (external smoothness/crystallinity, low surface charge) …