Journal article
Aging, frailty and age-related diseases
Abstract
The concept of frailty as a medically distinct syndrome has evolved based on the clinical experience of geriatricians and is clinically well recognizable. Frailty is a nonspecific state of vulnerability, which reflects multisystem physiological change. These changes underlying frailty do not always achieve disease status, so some people, usually very elderly, are frail without a specific life threatening illness. Current thinking is that not …
Authors
Fulop T; Larbi A; Witkowski JM; McElhaney J; Loeb M; Mitnitski A; Pawelec G
Journal
Biogerontology, Vol. 11, No. 5, pp. 547–563
Publisher
Springer Nature
Publication Date
October 2010
DOI
10.1007/s10522-010-9287-2
ISSN
1389-5729