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Second malignancy risk associated with treatment...
Journal article

Second malignancy risk associated with treatment of Hodgkin's lymphoma: meta-analysis of the randomised trials

Abstract

BACKGROUND: Despite several investigations, second malignancy risks (SMR) following radiotherapy alone (RT), chemotherapy alone (CT) and combined chemoradiotherapy (CRT) for Hodgkin's lymphoma (HL) remain controversial. PATIENTS AND METHODS: We sought individual patient data from randomised trials comparing RT versus CRT, CT versus CRT, RT versus CT or involved-field (IF) versus extended-field (EF) RT for untreated HL. Overall SMR (including …

Authors

Franklin J; Pluetschow A; Paus M; Specht L; Anselmo A-P; Aviles A; Biti G; Bogatyreva T; Bonadonna G; Brillant C

Journal

Annals of Oncology, Vol. 17, No. 12, pp. 1749–1760

Publisher

Elsevier

Publication Date

12 2006

DOI

10.1093/annonc/mdl302

ISSN

0923-7534