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De novo 1q32q44 duplication and distal 1q trisomy...
Journal article

De novo 1q32q44 duplication and distal 1q trisomy syndrome

Abstract

We report on an infant with minor anomalies and a de novo 1q duplication. The chromosomal abnormality was diagnosed prenatally after sonographic detection of cerebral ventriculomegaly and bilateral choroid plexus cysts in the fetus. The amniocentesis showed an abnormal male karyotype, 46,XY,dup(1)(q32q44), subsequently confirmed by fluorescence in situ hybridization using whole chromosome paint 1 and comparative genomic hybridization. The baby, …

Authors

Nowaczyk MJM; Bayani J; Freeman V; Watts J; Squire J; Xu J

Journal

American Journal of Medical Genetics Part A, Vol. 120A, No. 2, pp. 229–233

Publisher

Wiley

Publication Date

July 15, 2003

DOI

10.1002/ajmg.a.20028

ISSN

1552-4825