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Deviations from the expected relationship between...
Journal article

Deviations from the expected relationship between serum FGF23 and other markers in children with CKD: a cross-sectional study

Abstract

BackgroundHigh levels of fibroblast growth factor-23 (FGF23) are associated with mortality. In chronic kidney disease (CKD), FGF23 levels rise as renal function declines. We analyzed the contribution of laboratory values to the variance of FGF23 levels in relationship to a curve of expected FGF23 levels for a given GFR.MethodsFollowing approval by the research ethics boards, we measured FGF23, CysC eGFR, creatinine, urea, albumin, calcium, …

Authors

Liu D; Alvarez-Elías AC; Wile B; Belostotsky V; Filler G

Journal

BMC Nephrology, Vol. 18, No. 1,

Publisher

Springer Nature

Publication Date

December 2017

DOI

10.1186/s12882-017-0623-5

ISSN

1471-2369