Vitamin K for the Treatment of Asymptomatic Coagulopathy Associated with Oral Anticoagulant Therapy

Patients with asymptomatic elevated International Normalized Ratios (INRs) are commonly seen in practice, but there is no consensus on how best to manage this condition. Evidence suggests that low-dose (1 mg to 2.5 mg) oral vitamin K restores patients to INR values associated with a lower risk of hemorrhage more rapidly than discontinuing warfarin alone. Vitamin K therapy remains under-utilized despite evidence for its effectiveness. The …