Journal article
Triggering Receptor Expressed on Myeloid cells-1 (TREM-1) Modulates Immune Responses to Aspergillus fumigatus During Fungal Asthma in Mice
Abstract
Triggering receptor expressed on myeloid cells-1 (TREM-1) expression is increased during pulmonary fungal infection suggesting that this receptor might be involved in anti-fungal immune responses. To address the role of TREM-1 in a murine model of fungal allergic airway disease, A. fumigatus-sensitized CBA/J mice received by intratracheal injection a mixture of live A. fumigatus conidia and one of a control adenovirus vector (Ad70), an …
Authors
Buckland KF; Ramaprakash H; Murray LA; Carpenter KJ; Choi ES; Kunkel SL; Lukacs NW; Xing Z; Aoki N; Hartl D
Journal
Immunological Investigations, Vol. 40, No. 7-8, pp. 692–722
Publisher
Taylor & Francis
Publication Date
January 1, 2011
DOI
10.3109/08820139.2011.578270
ISSN
0882-0139
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Adaptor Proteins, Signal TransducingAnimalsAspergillosis, Allergic BronchopulmonaryAspergillus fumigatusAsthmaBronchial HyperreactivityBronchoalveolar Lavage FluidChemokinesCytokinesFemaleHumansLungMembrane GlycoproteinsMiceMice, Inbred C57BLMice, Inbred CBAReceptors, ImmunologicTriggering Receptor Expressed on Myeloid Cells-1