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Use of recombinant virus-vectored tuberculosis...
Conference

Use of recombinant virus-vectored tuberculosis vaccines for respiratory mucosal immunization

Abstract

Recombinant virus-vectored TB vaccines represent the most promising vaccine platform for boosting the protective immunity mediated by parenteral BCG prime immunization. A major advantage associated with virus-vectored vaccines is that they are potent respiratory mucosa-deliverable vaccines. A recombinant replication-deficient adenoviral (Ad) vector was engineered to express Mycobacterium tuberculosis (M.tb) Ag85A. Single administration of this …

Authors

Xing Z; Lichty BD

Volume

86

Pagination

pp. 211-217

Publisher

Elsevier

Publication Date

May 2006

DOI

10.1016/j.tube.2006.01.017

Conference proceedings

Tuberculosis

Issue

3-4

ISSN

1472-9792