Journal article
Protection against Methacholine Bronchoconstriction to Assess Relative Potency of Inhaled β2-Agonist
Abstract
The purposes of this study were to estimate the relative dose potency (RP) of two formulations of salbutamol pressurized metered-dose inhalers (Proventil-HFA and Ventolin-CFC MDIs) to protect against methacholine bronchoconstriction, to validate this method and provide recommendations. The protective effects of 100-, 200-, and 400-micrograms doses of Proventil-HFA were compared with the same doses of Ventolin-CFC in 18 adult asthmatics (mean …
Authors
PARAMESWARAN KN; INMAN MD; EKHOLM BP; MORRIS MM; SUMMERS E; O'BYRNE PM; HARGREAVE FE
Journal
American Journal of Respiratory and Critical Care Medicine, Vol. 160, No. 1, pp. 354–357
Publisher
American Thoracic Society
Publication Date
July 1, 1999
DOI
10.1164/ajrccm.160.1.9812035
ISSN
1073-449X