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The effect of cysteinyl leukotrienes on growth of...
Journal article

The effect of cysteinyl leukotrienes on growth of eosinophil progenitors from peripheral blood and bone marrow of atopic subjects

Abstract

BACKGROUND: The accumulation of eosinophils into the peripheral blood and airways of asthmatic subjects is, in part, dependent on cysteinyl leukotrienes (cysLTs). However, the effect of cysLTs on peripheral blood and bone marrow eosinophil pro-genitor cells in allergic subjects is not known. OBJECTIVE: The purpose of this study was to evaluate the effects of leukotriene (LT) D(4) and LTE(4) and the cysLT(1) receptor antagonist montelukast on …

Authors

Braccioni F; Dorman SC; O'Byrne PM; Inman MD; Denburg JA; Parameswaran K; Baatjes AJ; Foley R; Gauvreau GM

Journal

The Journal of Allergy and Clinical Immunology, Vol. 110, No. 1, pp. 96–101

Publisher

Elsevier

Publication Date

July 2002

DOI

10.1067/mai.2002.125000

ISSN

0091-6749