Journal article
The effects of chemotherapeutic agents on the regulation of thrombin on cell surfaces
Abstract
Thromboembolic disorders are common in cancer patients. Two major contributing factors are central venous catheters for drug delivery and the use of l-aparaginase, which decreases the plasma antithrombin level, but the causes of the hypercoagulable state in these patients are not fully understood. In this study, the T24/83 cell line was used as a model to investigate the effects of chemotherapeutic agents on cell surface thrombin regulation. …
Authors
Paredes N; Xu L; Berry LR; Chan AKC
Journal
British Journal of Haematology, Vol. 120, No. 2, pp. 315–324
Publisher
Wiley
Publication Date
January 2003
DOI
10.1046/j.1365-2141.2003.03971.x
ISSN
0007-1048