Journal article
Characterization of the prejunctional beta adrenoceptors in canine bronchial smooth muscle.
Abstract
Prejunctional beta adrenoceptors in canine bronchi (3rd to 6th order) were characterized by observing the effects of beta receptor agonists and antagonists on field stimulation-induced contractions and excitatory junction potentials (EJPs). Contractions were antagonized by norepinephrine (IC50 = 9.4 X 10(-7) M), isoproterenol (IC50 = 1.9 X 10(-8) M) or salbutamol (IC50 = 4.0 X 10(-8) M). EJPs were also decreased by all three agonists, with …
Authors
Janssen LJ; Daniel EE
Journal
Journal of Pharmacology and Experimental Therapeutics, Vol. 254, No. 2, pp. 741–749
Publisher
Elsevier
Publication Date
August 1990
DOI
10.1016/s0022-3565(25)12678-5
ISSN
0022-3565