Journal article
Responsiveness of canine bronchial vasculature to excitatory stimuli and to cooling
Abstract
Changes in bronchial vascular tone, in part due to cooling during ventilation, may contribute to altered control of airflow during airway inflammation, asthma, and exercise-induced bronchoconstriction. We investigated the responses of canine bronchial vasculature to excitatory stimuli and cooling. Electrical stimulation evoked contractions in only some (8 of 88) tissues; these were phentolamine sensitive and augmented by …
Authors
Janssen LJ; Lu-Chao H; Netherton S
Journal
American Journal of Physiology - Lung Cellular and Molecular Physiology, Vol. 280, No. 5, pp. l930–l937
Publisher
American Physiological Society
Publication Date
May 1, 2001
DOI
10.1152/ajplung.2001.280.5.l930
ISSN
1040-0605
Fields of Research (FoR)
Medical Subject Headings (MeSH)
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic AcidAdenosine TriphosphateAnimalsAnti-Inflammatory Agents, Non-SteroidalBronchiBronchial ArteriesCalciumCold TemperatureDogsDose-Response Relationship, DrugElectric StimulationEnzyme InhibitorsGenisteinIn Vitro TechniquesNitroargininePhentolamineProtein Kinase CProtein-Tyrosine KinasesTracheaVasoconstrictionVasoconstrictor AgentsVeins