Journal article
Determination of alpha-2-macroglobulin complexes by a new immuno-activity assay
Abstract
INTRODUCTION: Alpha-2-macroglobulin (α(2)M) is a broad specificity protease inhibitor which impacts several hemostatic pathways. Selective detection of various α(2)M complexes may be useful to define markers for the status of different hemostatic components. We present proof of principle for a novel assay to quantitatively measure α(2)M in complex with a variety of hemostatic factors.
MATERIALS AND METHODS: The assay makes use of the fact that …
Authors
Atkinson HM; Parmar N; Berry LR; Chan AKC
Journal
Thrombosis Research, Vol. 129, No. 5, pp. 635–640
Publisher
Elsevier
Publication Date
May 2012
DOI
10.1016/j.thromres.2011.07.029
ISSN
0049-3848