Journal article
Intestinal, Airway, and Cardiovascular Relaxant Activities of Thymoquinone
Abstract
Thymoquinone (TQ) is a bioactive component found in many medicinal herbs. In this study, we report the smooth and cardiac muscle relaxant activities of this compound. TQ concentration dependently suppressed spontaneously contracting rabbit jejunum while also relaxed high K(+)-(80 mM) induced contractions in jejunum and guinea-pig ileum, indicating activity at voltage-operated Ca(++) channels (VOCC). Further, TQ displaced Ca(++) …
Authors
Ghayur MN; Gilani AH; Janssen LJ
Journal
Evidence-based Complementary and Alternative Medicine, Vol. 2012, No. 1,
Publisher
Wiley
Publication Date
2012
DOI
10.1155/2012/305319
ISSN
1741-427X