Continuous, multimodal physiological monitoring is critical for managing chronic diseases and detecting infectious outbreaks; however, existing wearable solutions remain fragmented, often measuring isolated vital signs from multiple devices. This work presents WHeMo, a unified, chest-worn platform that integrates synchronized electrocardiogram (ECG), photoplethysmogram (PPG), inertial (IMU), temperature, and acoustic sensing into a single, low-cost device. This novel hardware fusion enables the simultaneous derivation of a comprehensive physiological profile: heart rate (HR) and variability (HRV), respiratory rate (RR), oxygen saturation (SpO₂), cuffless blood pressure (BP), body-temperature trends, cough frequency, and relative lung volume. Robust signal-processing pipelines incorporating adaptive filtering and sensor fusion ensure reliable operation under real-world, ambulatory conditions. Multi-level validation across benchmark datasets and volunteer recordings demonstrated consistently high accuracy, with mean absolute errors below 1 bpm for HR, below 1 breath/min for IMU-based respiration, approximately 1–1.5% for chest-mounted SpO₂, and 1–3 mmHg for cuffless BP across varied activity conditions. By consolidating cardiopulmonary and infection-related sensing, WHeMo uniquely supports the longitudinal tracking of chronic conditions such as heart failure and COPD while enabling automated surveillance of infectious-disease symptoms including cough, fever, and dyspnea. Its smartphone-based interface and reusable design facilitate scalable deployment for remote patient monitoring in home and tele-health settings, bridging a critical gap between clinical-grade assessment and practical, continuous wearable health monitoring.
