Concentration of Clindamycin in Human Bone

Abstract

Thirty patients undergoing total hip replacement received clindamycin beginning the day before surgery. Mean clindamycin concentrations during surgery were 7.33 +/- 3.37 mug/ml in serum and 2.63 +/- 1.76 mug/g in bone; mean ratio of bone-serum concentration was 0.40 +/- 0.30.

Authors

Nicholas P; Meyers BR; Levy RN; Hirschman SZ

Journal

Antimicrobial Agents and Chemotherapy, Vol. 8, No. 2, pp. 220–221

Publisher

American Society for Microbiology

Publication Date

August 1, 1975

DOI

10.1128/aac.8.2.220

ISSN

0066-4804

Associated Experts

Brandon Meyers

Associate Professor, Faculty of Health Sciences

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