Differences in codon usage between host-species-specific rabies virus clades are driven by UpA and purine content

Abstract

Abstract Viral genes sometimes use certain codons more than others due to their nucleotide content, translational efficiency, and selection pressure from the host immune system. The rabies virus (RABV) is a negative strand RNA virus which can infect a broad range of mammalian hosts, with many of its clades circulating predominantly in specific host species. Previous work on codon usage in RABV has focused only on broader viral …

Authors

Durrant R; Dushoff J; Arnold M; Cobbold C; Hampson K

Publication date

January 12, 2026

DOI

10.64898/2026.01.12.699068

Preprint server

openRxiv

Associated Experts

Jonathan Dushoff

Professor, Faculty of Science

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