Journal article
Simultaneous Measurement of 92 Serum Protein Biomarkers for the Development of a Multi-Protein Classifier for Ovarian Cancer Detection
Abstract
The best known ovarian cancer biomarker, CA125, is neither adequately sensitive nor specific for screening the general population. By using a combination of proteins for screening, it may be possible to increase the sensitivity and specificity over CA125 alone. In this study, we used Proseek Multiplex Oncology II plates to simultaneously measure the expression of 92 cancer-related proteins in serum using proximity extension assays. This …
Authors
Skubitz APN; Boylan KLM; Geschwind K; Cao Q; Starr TK; Geller MA; Celestino J; Bast RC; Lu KH; Koopmeiners JS
Journal
Cancer Prevention Research, Vol. 12, No. 3,
Publisher
American Association for Cancer Research (AACR)
Publication Date
March 1, 2019
DOI
10.1158/1940-6207.capr-18-0221
ISSN
1940-6207