Journal article
Cyclin G2 Suppresses Estrogen-Mediated Osteogenesis through Inhibition of Wnt/β-Catenin Signaling
Abstract
Estrogen plays an important role in the maintenance of bone formation, and deficiency in the production of estrogen is directly linked to postmenopausal osteoporosis. To date, the underlying mechanisms of estrogen-mediated osteogenic differentiation are not well understood. In this study, a pluripotent mesenchymal precursor cell line C2C12 was used to induce osteogenic differentiation and subjected to detection of gene expressions or to …
Authors
Gao J; Liu Q; Liu X; Ji C; Qu S; Wang S; Luo Y
Journal
PLOS ONE, Vol. 9, No. 3,
Publisher
Public Library of Science (PLoS)
DOI
10.1371/journal.pone.0089884
ISSN
1932-6203